Knee & joint regeneration
Your knee doesn't need replacing. It needs regenerating.
Passage 3 stem cells applied directly into the joint — for athletes, former athletes, and anyone told surgery is the only option. All-inclusive in Medellín, from $3,500 USD.
The science
How the cells work.
Cord stem cells deliver anti-inflammatory cytokines and anabolic signals that decrease synovial inflammation, modulate catabolic enzymes, and promote tissue repair — supporting cartilage, ligament, tendon and muscle healing and reducing symptomatic inflammation in degenerative or inflammatory joint conditions.
Self-check
This is for you if…
Recognize yourself in two or more? You're very likely a candidate.
You've tried cortisone, physical therapy or PRP — and the relief never lasts.
Your doctor mentioned knee or hip replacement, and you want to avoid major surgery.
A past injury (soccer, basketball, skiing, running) is still limiting you years later.
You want to get back to the activities you love — not just "manage" the pain.
You want to understand exactly what will be done, and why — before you commit to anything.
Sounds like you?
Send us your case and imaging. A specialist reviews it and tells you honestly whether you're a candidate — free, no obligation.
How we treat your knee
We don't mask the pain — we target the source.
Under ultrasound guidance, we apply 50 million Passage 3 Wharton's Jelly stem cells directly into the joint, in the operating room, under mild sedation or local anesthesia. The cells go exactly where the damage is. Combined with our full protocol — detox IV, hyperbaric chamber, exosomes — your body gets everything it needs to rebuild.
See the full protocolAuthority
Why we're experts in this.
Joint and spine work is what our team does most — precise intra-articular application is our specialty, not a side service.
Patient stories
The goal is always the same: your life, back.
Most people come to us after being told surgery — or simply “learning to live with it” — was their only option. We’re gathering their video stories from patients around the world. In the meantime, hear directly from people who’ve already made the journey.
Safety & facilities
A real operating room. A real medical team.
Procedures are performed in a fully-equipped OR inside the same building as your hotel, with ultrasound guidance — to the standards you'd expect anywhere in the world.
See the facilities

Everything included — cells, procedure, OR, hotel, transfers, therapy and follow-up.
The same treatment in the US, where available, runs $20,000+.
See full pricingKnee FAQ
Quick answers.
Life after treatment
Back to the trail — and everything you paused.
Patients who walked in facing a knee replacement have gone back to hiking, cycling and keeping up with their grandkids. Regeneration isn't just less pain — it's your life, resumed.
Book your consultation
Google reviews
Loved by patients worldwide.
Find out if you're a candidate.
A specialist will give you an honest read on your case — no commitment.