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Knee & joint regeneration

Your knee doesn't need replacing. It needs regenerating.

Passage 3 stem cells applied directly into the joint — for athletes, former athletes, and anyone told surgery is the only option. All-inclusive in Medellín, from $3,500 USD.

Knee joint regenerating with Passage 3 stem cells

The science

How the cells work.

Cord stem cells deliver anti-inflammatory cytokines and anabolic signals that decrease synovial inflammation, modulate catabolic enzymes, and promote tissue repair — supporting cartilage, ligament, tendon and muscle healing and reducing symptomatic inflammation in degenerative or inflammatory joint conditions.

Passage 3 cells
Youngest, most potent MSCs
Imaging-guided
Ultrasound + ultrasound
Specialist MDs
Not a generalist clinic
8,000+ procedures
Under imaging guidance
Dedicated bilingual care
Everything in clear English

Self-check

This is for you if…

Recognize yourself in two or more? You're very likely a candidate.

You've tried cortisone, physical therapy or PRP — and the relief never lasts.

Your doctor mentioned knee or hip replacement, and you want to avoid major surgery.

A past injury (soccer, basketball, skiing, running) is still limiting you years later.

You want to get back to the activities you love — not just "manage" the pain.

You want to understand exactly what will be done, and why — before you commit to anything.

Sounds like you?

Send us your case and imaging. A specialist reviews it and tells you honestly whether you're a candidate — free, no obligation.

How we treat your knee

We don't mask the pain — we target the source.

Under ultrasound guidance, we apply 50 million Passage 3 Wharton's Jelly stem cells directly into the joint, in the operating room, under mild sedation or local anesthesia. The cells go exactly where the damage is. Combined with our full protocol — detox IV, hyperbaric chamber, exosomes — your body gets everything it needs to rebuild.

See the full protocol
Detox IV preparation
Hyperbaric oxygen sessions
Guided intra-articular application (50–100M cells)
Exosomes to amplify healing
Guided recovery & follow-up

Authority

Why we're experts in this.

8,000+
procedures under imaging guidance
50–100M
cells applied per joint

Joint and spine work is what our team does most — precise intra-articular application is our specialty, not a side service.

Patient stories

The goal is always the same: your life, back.

Most people come to us after being told surgery — or simply “learning to live with it” — was their only option. We’re gathering their video stories from patients around the world. In the meantime, hear directly from people who’ve already made the journey.

Watch patient stories
Dra. Diana Reyes

Your team

Specialists, not generalists.

Dr. Diana Reyes (anesthesiologist & pain specialist) leads your care, alongside a sports medicine physician.

Board-certified · Regenerative medicine

Safety & facilities

A real operating room. A real medical team.

Procedures are performed in a fully-equipped OR inside the same building as your hotel, with ultrasound guidance — to the standards you'd expect anywhere in the world.

See the facilities
Quirófano Stemcells Colombia
Aplicación guiada por imagen
Knee & joint treatment
From $3,500 USD

Everything included — cells, procedure, OR, hotel, transfers, therapy and follow-up.

The same treatment in the US, where available, runs $20,000+.

See full pricing

Knee FAQ

Quick answers.

The application is done under mild sedation or local anesthesia. Most patients describe mild soreness afterward, not pain.
Most patients notice changes within 3–6 months as the tissue regenerates.
About 5 days. We handle the logistics — airport pickup, hotel, transfers and follow-up.
No honest clinic guarantees results. What we guarantee is the quality of the cells, the precision of the application, and that we'll be with you the whole way.

Life after treatment

Back to the trail — and everything you paused.

Patients who walked in facing a knee replacement have gone back to hiking, cycling and keeping up with their grandkids. Regeneration isn't just less pain — it's your life, resumed.

Book your consultation
Active patient hiking after knee regeneration

Google reviews

Loved by patients worldwide.

Find out if you're a candidate.

A specialist will give you an honest read on your case — no commitment.

Chat with us