As we age, our cells undergo a process known as cellular senescence, where they lose the ability to function properly and can even impair the surrounding healthy cells. These “aged” or senescent cells contribute to the aging process and are linked to various age-related diseases. However, recent research has unveiled the rejuvenating potential of stem cells and senolytic compounds—anti-aging agents that target and eliminate senescent cells—offering hope for alleviating the symptoms of aging.
Stem cells and senolytic compounds hold promise as powerful anti-aging therapies because they have the ability to repair damaged tissues and restore cellular and organ function . The potential benefits of stem cell therapy and senolytic compounds for aging include improvements in skin health, enhanced tissue repair, reduced inflammation, and overall rejuvenation of cellular performance.
As we age, the number and functionality of our stem cells decline, slowing down the body’s ability to repair tissues and increasing vulnerability to diseases. By transplanting healthy stem cells, researchers aim to restore regenerative capacity and mitigate the effects of aging.
In addition, rejuvenating compounds such as NAD (Nicotinamide Adenine Dinucleotide), metformin, and estradiol are being studied for their ability to slow down or even reverse the senescence process. These compounds may offer new ways to fight age-related decline, improving quality of life and extending healthspan.
By harnessing the potential of stem cells and senolytic compounds, we may be able to slow the aging process and perhaps even turn back the biological clock, inching closer to our very own version of Benjamin Button.
by Lina Palacio PhDhttps://ca.linkedin.com/in/lina-palacio